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Mouse Anti-CA7 Recombinant Antibody (CBLC044-LY) (CBMAB-C9591-LY)

The product is antibody recognizes CA7. The antibody CBLC044-LY immunoassay techniques such as: WB.
See all CA7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLC044-LY
Antibody Isotype
IgG1, κ
Application
E, WB, IF, IP

Basic Information

Immunogen
Amino acids 1-90 mapping at the N-terminus of CA VII of human origin.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
0.09% sodium azide
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
carbonic anhydrase VII
Introduction
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.
Entrez Gene ID
766
UniProt ID
P43166
Alternative Names
CA-VII, CAVII
Function
Reversible hydration of carbon dioxide.
Biological Process
Bicarbonate transport Source: Reactome
One-carbon metabolic process Source: GO_Central
Positive regulation of cellular pH reduction Source: Ensembl
Positive regulation of synaptic transmission, GABAergic Source: Ensembl
Regulation of chloride transport Source: Ensembl
Regulation of intracellular pH Source: GO_Central
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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