Mouse Anti-CAB39L Recombinant Antibody (CBLC046-LY) (CBMAB-C9599-LY)

Name: Mouse Anti-CAB39L Recombinant Antibody (CBLC046-LY)
SKU: CBMAB-C9599-LY
Rating: 5 (1 reviews)

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Published Data

Mouse Anti-CAB39L Recombinant Antibody (CBLC046-LY) (CBMAB-C9599-LY) in WB

Overexpression of CAB39L induced PGC1α phosphorylation, whilst CAB39L knockdown produced an opposite effect. ...View More

Li, W., Wong, C. C., Zhang, X., Kang, W., Nakatsu, G., Zhao, Q., ... & Yu, J. (2018). CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis. Oncogene, 37(50), 6383-6398.

Mouse Anti-CAB39L Recombinant Antibody (CBLC046-LY) (CBMAB-C9599-LY) in IP

Co-immunoprecipitation (Co-IP) of CAB39L with anti-Flag and anti-CAB39L in AGS-CAB39L and MKN74 cells, respectively, identified LKB1 and STRAD as the binding partners of CAB39L. ...View More

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBLC046-LY

Application

E, WB, IF, IP, P

Immunogen

Recombinant CAB39L of human origin.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:100-1:1,000
IHC-P	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

0.09% sodium azide

Concentration

0.1 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

calcium binding protein 39-like

Introduction

CAB39L (Calcium Binding Protein 39 Like) is a Protein Coding gene. Among its related pathways are RET signaling and mTOR signalling. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is CAB39.

Entrez Gene ID

81617

UniProt ID

Q9H9S4

Alternative Names

Calcium Binding Protein 39 Like; Mo25-Like Protein; Antigen MLAA-34; MO25beta; Calcium Binding Protein 39-Like; Calcium-Binding Protein 39-Like;

Function

Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity).

Biological Process

Cell cycle arrest Source: Reactome
Intracellular signal transduction Source: GO_Central

Cellular Location

Cytosol

Pulito, C., Mori, F., Sacconi, A., Goeman, F., Ferraiuolo, M., Pasanisi, P., ... & Blandino, G. (2017). Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities. Cell discovery, 3(1), 1-19.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-CAB39L Recombinant Antibody (3B11-1A4) (CAT#: CBMAB-C5689-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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