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Mouse Anti-CALY Recombinant Antibody (G-8) (CBMAB-1292-CN)

This product is a mouse antibody that recognizes CALY of human. The antibody G-8 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all CALY antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
G-8
Antibody Isotype
IgG2a
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.2 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Calcyon Neuron Specific Vesicular Protein
Introduction
The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs.
Entrez Gene ID
50632
UniProt ID
Q9NYX4
Alternative Names
NSG3; DRD1IP
Function
Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
Biological Process
Anterograde axonal transport Source: Ensembl
Clathrin coat assembly Source: UniProtKB
Dopamine receptor signaling pathway Source: InterPro
Endosomal transport Source: GO_Central
Positive regulation of clathrin coat assembly Source: Ensembl
Positive regulation of endocytosis Source: UniProtKB
Positive regulation of retrograde axon cargo transport Source: Ensembl
Postsynaptic neurotransmitter receptor internalization Source: Ensembl
Cellular Location
Cell membrane; Cytoplasmic vesicle membrane
Topology
Extracellular: 1-87 aa
Helical: 88-108 aa
Cytoplasmic: 109-217 aa
PTM
Glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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