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Rabbit Anti-CaMKII alpha and CaMKII beta (phospho T286) Recombinant Antibody (BA0174) (CBMAB-0141CQ)

This product is a rabbit antibody that recognizes CaMKII alpha and CaMKII beta (phospho T286). The antibody BA0174 can be used for immunoassay techniques such as: IF, WB.
See all CAMK2A and CAMK2B antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
BA0174
Antibody Isotype
IgG
Application
IF, WB

Basic Information

Immunogen
Synthetic peptide from Human CaMKII alpha + CaMKII beta (phospho T286) aa 250-350
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Introduction
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Entrez Gene ID
815
UniProt ID
Q9UQM7
Alternative Names
Calcium/Calmodulin-Dependent Protein Kinase II Alpha; Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase) II Alpha; Calcium/Calmodulin-Dependent Protein Kinase Type II Alpha Chain; Calcium/Calmodulin-Dependent Protein Kinase II Alpha-B Subunit; CaM Kinase II Alpha Subunit; CaM Kinase II Subunit Alpha; CaM-Kinase II Alpha Chain; CaMK-II Alpha Subunit; CaMK-II Subunit Alpha; EC 2.7.11.17; CAMKA; CaMKIINalpha; EC 2.7.11; KIAA0968
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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