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Mouse Anti-HAUS1 Recombinant Antibody (1E3) (CBMAB-A1159-LY)

The product is antibody recognizes CCDC5. The antibody 1E3 immunoassay techniques such as: WB, ELISA.
See all HAUS1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1E3
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
CCDC5 (NP_612452.1, 179 a.a. ~ 278 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
HAUS Augmin Like Complex Subunit 1
Entrez Gene ID
115106
UniProt ID
Q96CS2
Alternative Names
FLJ21094; FLJ40084; HEI-C; HsT1461
Function
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Biological Process
Cell division Source: UniProtKB-KW
Centrosome cycle Source: UniProtKB
Spindle assembly Source: UniProtKB
Cellular Location
Centrosome; Spindle; Spindle pole; Cytoplasm. Localizes with the spindle poles in mitotic cells. In metaphase, localizes to the mitotic asters and is highly punctate on the microtubule array. During later stages of mitosis, remains on the spindle but is not present at the interzone, and is finally observed at the microtubule bundles proximal to the midbody, clearly excluded from the midbody. In contrast, does not colocalize with the tubulin cytoskeleton in interphase cells. In interphase, localized at the centrosome and diffusely in the cytoplasm. Localizes to mitotic spindle microtubules.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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