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Mouse Anti-CCNG2 Recombinant Antibody (1F9-C11) (CBMAB-C4103-LY)

This product is antibody recognizes CCNG2. The antibody 1F9-C11 immunoassay techniques such as: WB, IP, IF, IHC-P, ELISA.
See all CCNG2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F9-C11
Antibody Isotype
IgG
Application
WB, IP, IF, IHC-P, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
cyclin G2
Introduction
CCNG2 (Cyclin G2) is a Protein Coding gene. Among its related pathways are DNA Damage Response (only ATM dependent) and Mitotic G1-G1/S phases. An important paralog of this gene is CCNG1.
Entrez Gene ID
901
UniProt ID
Q16589
Alternative Names
Cyclin G2; Cyclin-G2;
Function
May play a role in growth regulation and in negative regulation of cell cycle progression.
Biological Process
Cell division Source: UniProtKB-KW
Mitotic cell cycle phase transition Source: GO_Central
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: GO_Central
Cellular Location
Cytoplasm

Sun, M., Gao, J., Meng, T., Liu, S., Chen, H., Liu, Q., ... & Luo, Y. (2021). Cyclin G2 upregulation impairs migration, invasion, and network formation through RNF123/Dvl2/JNK signaling in the trophoblast cell line HTR8/SVneo, a possible role in preeclampsia. The FASEB Journal, 35(2), e21169.

Di Zhang, J. L. G., Zhao, C. Y., Wang, D. N., Xing, X. S., Hou, X. Y., Wang, S. S., ... & Luo, Y. (2021). Cyclin G2 promotes the formation of smooth muscle cells derived foam cells in atherosclerosis via PP2A/NF-κB/LOX-1 pathway. Annals of Translational Medicine, 9(6).

Huang, Q., Hsueh, C. Y., Guo, Y., Wu, X. F., Li, J. Y., & Zhou, L. (2020). Lack of miR‐1246 in small extracellular vesicle blunts tumorigenesis of laryngeal carcinoma cells by regulating Cyclin G2. IUBMB life, 72(7), 1491-1503.

Zhao, C., Gao, J., Li, S., Liu, Q., Hou, X., Xing, X., ... & Luo, Y. (2020). Cyclin G2 regulates canonical Wnt signalling via interaction with Dapper1 to attenuate tubulointerstitial fibrosis in diabetic nephropathy. Journal of cellular and molecular medicine, 24(5), 2749-2760.

Sun, M., Liu, S., Gao, J., Meng, T., Xing, X., Chen, C., ... & Luo, Y. (2020). Cyclin G2 Is Involved in the Proliferation of Placental Trophoblast Cells and Their Interactions with Endothelial Cells. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 26, e926414-1.

Salem, M., Shan, Y., Bernaudo, S., & Peng, C. (2019). miR-590-3p targets cyclin G2 and FOXO3 to promote ovarian cancer cell proliferation, invasion, and spheroid formation. International journal of molecular sciences, 20(8), 1810.

Li, S., Gao, J., Zhuang, X., Zhao, C., Hou, X., Xing, X., ... & Luo, Y. (2019). Cyclin G2 inhibits the warburg effect and tumour progression by suppressing LDHA phosphorylation in glioma. International journal of biological sciences, 15(3), 544.

Zhao, C., Gao, J., Li, S., Liu, Q., Hou, X., Liu, S., ... & Luo, Y. (2018). Cyclin G2 suppresses glomerulosclerosis by regulating canonical Wnt signalling. BioMed research international, 2018.

Li, X. J., Ren, Z. J., Tang, J. H., & Yu, Q. (2017). Exosomal MicroRNA MiR-1246 promotes cell proliferation, invasion and drug resistance by targeting CCNG2 in breast cancer. Cellular Physiology and Biochemistry, 44(5), 1741-1748.

Bernaudo, S., Khazai, S., Honarparvar, E., Kopteva, A., & Peng, C. (2017). Epidermal growth factor promotes cyclin G2 degradation via calpain-mediated proteolysis in gynaecological cancer cells. PLoS One, 12(6), e0179906.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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