Sign in or Register   Sign in or Register
  |  

Rat Anti-CCT4 Recombinant Antibody (CBYJT-1072) (CBMAB-T0082-YJ)

Provided herein is a Rat monoclonal antibody, which binds to CCT4 (Chaperonin Containing TCP1 Subunit 4). The antibody can be used for immunoassay techniques, such as GS, IP, WB.
See all CCT4 antibodies

Summary

Host Animal
Rat
Specificity
Human, Mouse, Cattle
Clone
CBYJT-1072
Antibody Isotype
IgG2b
Application
GS, IP, WB

Basic Information

Specificity
Human, Mouse, Cattle
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Preservative
0.08% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Chaperonin Containing TCP1 Subunit 4
Introduction
CCT4 (Chaperonin Containing TCP1 Subunit 4) is a component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex it may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Entrez Gene ID
Human10575
Mouse12464
Cattle613336
UniProt ID
HumanP50991
MouseP80315
CattleF1N0E5
Alternative Names
Chaperonin Containing TCP1 Subunit 4; Chaperonin Containing TCP1, Subunit 4 (Delta); Stimulator Of TAR RNA-Binding; TCP-1-Delta; CCT-DELTA; Cctd; SRB; Chaperonin Containing T-Complex Polypeptide 1, Delta Subunit; T-Complex Protein 1 Subunit Delta
Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444).
The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).
As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638).
The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Biological Process
Binding of sperm to zona pellucida Source: Ensembl
Positive regulation of establishment of protein localization to telomere Source: BHF-UCL
Positive regulation of protein localization to Cajal body Source: BHF-UCL
Positive regulation of telomerase activity Source: BHF-UCL
Positive regulation of telomerase RNA localization to Cajal body Source: BHF-UCL
Positive regulation of telomere maintenance via telomerase Source: BHF-UCL
Protein folding Source: FlyBase
Protein stabilization Source: BHF-UCL
scaRNA localization to Cajal body Source: BHF-UCL
Toxin transport Source: Ensembl
Cellular Location
Cytoplasm; Centrosome; Cilium basal body; Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rat Anti-CCT4 Recombinant Antibody (CBYJT-1072)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare