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Rat Anti-CD300LB Recombinant Antibody (CBYY-C0027) (CBMAB-C0073-YY)


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Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYY-C0027
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CD300b/LMIR5 Ile18-Tyr157.
Host Species
Rat
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, trehalose
Preservative
None
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CD300 Molecule Like Family Member B
Entrez Gene ID
124599
UniProt ID
A8K4G0
Function
Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.
Biological Process
Innate immune response Source: Reactome
Regulation of immune response Source: Reactome
Cellular Location
Cell membrane
Topology
Extracellular: 18-151
Helical: 152-172
Cytoplasmic: 173-201
PTM
Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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