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Rat Anti-CD300LB Recombinant Antibody (CBYY-C0027) (CBMAB-C0073-YY)

This product is rat antibody that recognizes CD300LB. The antibody CBYY-C0027 can be used for immunoassay techniques such as: WB, IHC-P, FC, ELISA, IF
See all CD300LB antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYY-C0027
Antibody Isotype
IgG2b
Application
WB, IHC-P, FC, ELISA, IF

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CD300b/LMIR5 Ile18-Tyr157
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, trehalose
Preservative
PBS, 5% trehalose
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CD300 Molecule Like Family Member B
Entrez Gene ID
UniProt ID
Alternative Names
Cytotoxic T-Lymphocyte Associated Protein 4; Insulin-Dependent Diabetes Mellitus 12; Celiac Disease 3; CTLA-4; CD152; Ligand And Transmembrane Spliced Cytotoxic T Lymphocyte Associated Antigen 4; Cytotoxic T Lymphocyte Associated Antigen 4 Short Spliced Form; Cytotoxic T-Lymphocyte-Associated Serine Esterase-4; Cytotoxic T-Lymphocyte-Associated Antigen 4; Cytotoxic T-Lymphocyte Protein 4;
Function
Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.
Biological Process
Innate immune response Source: Reactome
Regulation of immune response Source: Reactome
Cellular Location
Cell membrane
Topology
Extracellular: 18-151
Helical: 152-172
Cytoplasmic: 173-201
PTM
Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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