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Mouse Anti-CDC42EP1 Recombinant Antibody (C5649) (CBMAB-C5649-LY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
C5649
Antibody Isotype
IgG1, κ
Application
WB, IF, IP, ELISA

Basic Information

Immunogen
Amino acids 126-219 mapping within an internal region of MSE55 of human.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CDC42 effector protein (Rho GTPase binding) 1
Introduction
CDC42EP1 (CDC42 Effector Protein 1) is a Protein Coding gene. Among its related pathways are ERK Signaling and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include GTP-Rho binding. An important paralog of this gene is CDC42EP4.
Entrez Gene ID
11135
UniProt ID
Q00587
Alternative Names
CDC42 Effector Protein 1; Binder Of Rho GTPases 5; 55 KDa Bone Marrow Stromal/Endothelial Cell Protein; CDC42 Effector Protein (Rho GTPase Binding) 1; Serum Constituent Protein; Serum Protein MSE55; BORG5; MSE55; CEP1;
Function
Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.
Biological Process
Positive regulation of actin filament polymerization Source: GO_Central
Positive regulation of pseudopodium assembly Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Rho protein signal transduction Source: GO_Central
Cellular Location
Cytoskeleton; Endomembrane system
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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