Mouse Anti-Cdc42EP4 Recombinant Antibody (CBYY-C1688) (CBMAB-C3126-YY)

Name: Mouse Anti-Cdc42EP4 Recombinant Antibody (CBYY-C1688)
SKU: CBMAB-C3126-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-C1688

Application

ELISA, WB

Immunogen

CDC42EP4 (163 a.a. ~ 225 a.a) partial recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

CDC42 Effector Protein 4

Entrez Gene ID

23580

UniProt ID

Q9H3Q1

Alternative Names

Cadherin 1; Cadherin 1, Type 1, E-Cadherin (Epithelial); Epithelial Cadherin; E-Cadherin; CAM 120/80; Uvomorulin; CDHE; UVO; Calcium-Dependent Adhesion Protein, Epithelial; Cadherin 1, E-Cadherin (Epithelial);

Function

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.

Biological Process

Cellular response to interferon-gamma Source: Ensembl
Positive regulation of actin filament polymerization Source: GO_Central
Positive regulation of pseudopodium assembly Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Rho protein signal transduction Source: GO_Central

Cellular Location

Cytoskeleton; Endomembrane system

Ageta-Ishihara, N., Konno, K., Yamazaki, M., Abe, M., Sakimura, K., Watanabe, M., & Kinoshita, M. (2018). CDC42EP4, a perisynaptic scaffold protein in Bergmann glia, is required for glutamatergic tripartite synapse configuration. Neurochemistry international, 119, 190-198.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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