Mouse Anti-CDH16 Recombinant Antibody (CBT3873) (V2LY-0625-LY147)

Name: Mouse Anti-CDH16 Recombinant Antibody (CBT3873)
SKU: V2LY-0625-LY147
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-CDH16 Recombinant Antibody (CBT3873) (V2LY-0625-LY147) in WB

Mouse Anti-CDH16 Recombinant Antibody (CBT3873) (V2LY-0625-LY147) in IF

Mouse Anti-CDH16 Recombinant Antibody (CBT3873) (V2LY-0625-LY147) in FC

Mouse Anti-CDH16 Recombinant Antibody (CBT3873) (V2LY-0625-LY147) in IHC

Mouse Anti-CDH16 Recombinant Antibody (CBT3873) (V2LY-0625-LY147) in ELISA

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBT3873

Antibody Isotype

IgG1

Application

WB, IHC, ICC, FC

Basic Information

Immunogen

Purified recombinant fragment of human CDH16 (AA: EX(558-721)) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
IHC-P	1:200-1:1,000
ICC	1:200-1:1,000
FC	1:200-1:400
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID

1014

UniProt ID

O75309

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Biological Process

Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules Source: Ensembl
Cell adhesion Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro

Cellular Location

Cell membrane

Topology

Extracellular: 19-786
Helical: 787-807
Cytoplasmic: 808-829

More Infomation

References

Thomson, R. B., Dynia, D. W., Burlein, S., Thomson, B. R., Booth, C. J., Knauf, F., ... & Aronson, P. S. (2021). Deletion of Cdh16 Ksp-cadherin leads to a developmental delay in the ability to maximally concentrate urine in mouse. American Journal of Physiology-Renal Physiology, 320(6), F1106-F1122.

Li, P., Wu, Q., Sun, Y., Pan, X., Han, Y., Ye, B., ... & Zheng, Z. (2019). Downregulation of CDH16 in papillary thyroid cancer and its potential molecular mechanism analysed by qRT-PCR, TCGA and in silico analysis. Cancer management and research, 11, 10719.

Ye, J., He, J., & Li, N. (2019). Molecular identification and characterization of pig's Cdh16 gene. Gene Reports, 14, 30-35.

Koumarianou, P., Goméz-López, G., & Santisteban, P. (2017). Pax8 controls thyroid follicular polarity through cadherin-16. Journal of cell science, 130(1), 219-231.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Mouse Anti-CDH16 Recombinant Antibody (C10801) (CAT#: CBMAB-C10801-LY)

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Mouse Anti-CDH16 Recombinant Antibody (K0258) (CAT#: CBMAB-K0258-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote
Second antibody and isotype control

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