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Mouse Anti-CDH19 Recombinant Antibody (CBFYC-1556) (CBMAB-C1615-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-1556
Antibody Isotype
IgG1, κ
Application
WB, ELISA, IF, IP

Basic Information

Immunogen
Amino acids 365-397 within an extracellular domain of cadherin-19 of human.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 231-340

Target

Full Name
Cadherin 19
Introduction
CDH19 (Cadherin 19) is a Protein Coding gene. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH7.
Entrez Gene ID
28513
UniProt ID
Q9H159
Alternative Names
Cadherin 19; Cadherin 19, Type 2; CDH7L2; Cadherin-19; CDH7
Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Biological Process
Adherens junction organization Source: GO_Central
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules Source: GO_Central
Cell-cell adhesion via plasma-membrane adhesion molecules Source: GO_Central
Cell-cell junction assembly Source: GO_Central
Cell morphogenesis Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Multicellular organism development Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 44-596
Helical: 597-617
Cytoplasmic: 618-772
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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