Mouse Anti-CENPP Recombinant Antibody (CBYY-C1873) (CBMAB-C3311-YY)

Name: Mouse Anti-CENPP Recombinant Antibody (CBYY-C1873)
SKU: CBMAB-C3311-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-C1873

Application

ELISA, WB

Immunogen

CENPP (N1 a.a. ~ 98 a.a) partial recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Centromere Protein P

Entrez Gene ID

401541

UniProt ID

Q6IPU0

Alternative Names

Complement Factor D; Properdin Factor D; Adipsin; D Component Of Complement (Adipsin); C3 Convertase Activator; EC 3.4.21.46; PFD;

Function

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.

Biological Process

CENP-A containing nucleosome assembly Source: Reactome
Mitotic spindle organization Source: Reactome

Cellular Location

Nucleus; Centromere. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.

Lee, S. H., Rodriguez, L. R., Majumdar, R., De Marval, P. L. M., & Rodriguez‑Puebla, M. L. (2021). CDK4 has the ability to regulate Aurora B and Cenpp expression in mouse keratinocytes. Oncology Letters, 22(4), 1-8.

Chen, H., Pu, S., Yu, S., Liao, X., He, J., & Zhang, H. (2021). A nomogram based on CENPP expression for survival prediction in breast cancer. Gland Surgery, 10(6), 1874.

Lee, S. H., Rodriguez, L. R., de Marval, P. L. M., & Rodriguez-Puebla, M. L. (2020). Emergent functions of cyclin-dependent kinase 4 regulating aurora b and cenpp transcription.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

CENPP Matched Antibody Pair (258) (CAT#: APMAB-258LY)

CENPP Matched Antibody Pair (259) (CAT#: APMAB-259LY)

Related Products

CENPP Matched Antibody Pair (258) (CAT#: APMAB-258LY)

CENPP Matched Antibody Pair (259) (CAT#: APMAB-259LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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