Mouse Anti-CETN3 Recombinant Antibody (CBYY-C1896) (CBMAB-C3334-YY)

Name: Mouse Anti-CETN3 Recombinant Antibody (CBYY-C1896)
SKU: CBMAB-C3334-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-C1896

Application

Immunogen

Full length human recombinant protein of human CETN3.

Host Species

Mouse

Specificity

Human, Mouse

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Centrin 3

Entrez Gene ID

1070

UniProt ID

O15182

Alternative Names

Cystic Fibrosis Transmembrane Conductance Regulator; Channel Conductance-Controlling ATPase; CAMP-Dependent Chloride Channel; EC 3.6.3.49; ABCC7; Cystic Fibrosis Transmembrane Conductance Regulator, ATP-Binding Cassette (Sub-Family C, Member 7); Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7); Cystic Fibrosis Transmembrane Conductance Regulating; ATP-Binding Cassette Sub-Family C, Member 7;

Function

Plays a fundamental role in microtubule-organizing center structure and function.
As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.

Biological Process

Cell division Source: UniProtKB-KW
Centrosome cycle Source: ProtInc
mRNA transport Source: UniProtKB-KW
Protein transport Source: UniProtKB-KW

Cellular Location

Centrosome; Centriole; Nucleolus; Nucleus envelope; Nuclear pore complex. Centrosome of interphase and mitotic cells (PubMed:9256449). Localizes to centriole distal lumen (PubMed:26337392). Localization at the nuclear pore complex requires NUP153 and TPR (PubMed:23591820).

Ying, G., Frederick, J. M., & Baehr, W. (2019). Deletion of both centrin 2 (CETN2) and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors. Journal of Biological Chemistry, 294(11), 3957-3973.

Ying, G., Frederick, J. M., & Baehr, W. (2019). Germline deletion of both CETN2 and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors. Investigative Ophthalmology & Visual Science, 60(9), 3977-3977.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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