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Mouse Anti-CHERP (AA 795-883) Recombinant Antibody (CBFYC-1821) (CBMAB-C1884-FY)

This product is mouse antibody that recognizes CHERP. The antibody CBFYC-1821 can be used for immunoassay techniques such as: ELISA, WB.
See all CHERP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-1821
Antibody Isotype
IgG2b, k
Application
ELISA, WB

Basic Information

Immunogen
CHERP partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: GSNSAPPIPD SRLGEENKGH QMLVKMGWSG SGGLGAKEQG IQDPIKGGDV RDKWDQYKGV GVALDDPYEN YRRNKSYSFI ARMKARDEC
Specificity
Human
Antibody Isotype
IgG2b, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 795-883

Target

Full Name
calcium homeostasis endoplasmic reticulum protein
Introduction
CHERP (Calcium Homeostasis Endoplasmic Reticulum Protein) is a Protein Coding gene. Diseases associated with CHERP include Autosomal Dominant Cerebellar Ataxia. Among its related pathways are Gene Expression and mRNA Splicing-Major Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding.
Entrez Gene ID
10523
UniProt ID
Q8IWX8
Alternative Names
Calcium Homeostasis Endoplasmic Reticulum Protein; ERPROT 213-21; SCAF6; SR-Related CTD Associated Factor 6; SR-Related CTD-Associated Factor 6; Protein With Polyglutamine Repeat
Function
Involved in calcium homeostasis, growth and proliferation.
Biological Process
Cellular calcium ion homeostasis Source: MGI
mRNA splicing, via spliceosome Source: Reactome
Negative regulation of cell population proliferation Source: MGI
Nervous system development Source: ProtInc
Positive regulation of calcineurin-NFAT signaling cascade Source: UniProtKB
Release of sequestered calcium ion into cytosol Source: UniProtKB
Cellular Location
Endoplasmic reticulum; Cytoplasm; Perinuclear region. Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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