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Mouse Anti-CLASRP Recombinant Antibody (CBXS-2191) (CBMAB-S4953-CQ)

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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBXS-2191
Antibody Isotype
IgG2a, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 28-152 mapping near the N-terminus of SFRS16 of human.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CLK4 Associating Serine/Arginine Rich Protein
Introduction
CLASRP (CLK4 Associating Serine/Arginine Rich Protein) is a Protein Coding gene. Diseases associated with CLASRP include Charcot-Marie-Tooth Disease, Axonal, Type 2D. Among its related pathways are mRNA Splicing - Major Pathway.
Entrez Gene ID
Human11129
Mouse53609
Rat499390
UniProt ID
HumanQ8N2M8
MouseQ8CFC7
RatQ5HZB6
Alternative Names
CLK4 Associating Serine/Arginine Rich Protein; CLK4-Associating Serine/Arginine Rich Protein; Splicing Factor, Arginine/Serine-Rich 16; Clk4 Associating SR-Related Protein; SFRS16; SWAP2;
Function
Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity).
Biological Process
mRNA processing Source: UniProtKB-KW
RNA splicing Source: UniProtKB-KW
Cellular Location
Nucleus
PTM
Phosphorylated in vitro by CLK4.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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