Mouse Anti-CLEC2A Recombinant Antibody (CBYY-C0561) (V2LY-1206-LY105)

Name: Mouse Anti-CLEC2A Recombinant Antibody (CBYY-C0561)
SKU: V2LY-1206-LY105
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-C0561

Application

WB, IHC

Immunogen

Recombinant human CLEC-2A, Trp49-Leu174.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	0.5 µg/ml
IHC	8-25 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, Trehalose

Preservative

None

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

C-Type Lectin Domain Family 2 Member A

Entrez Gene ID

387836

UniProt ID

Q6UVW9

Function

Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti-apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity.

Biological Process

Natural killer cell mediated cytotoxicity Source: UniProtKB

Cellular Location

Cell membrane

Topology

Cytoplasmic: 1-27
Helical: 28-48
Extracellular: 49-174

PTM

N-glycosylated.

Sung, P. S., & Hsieh, S. L. (2019). CLEC2 and CLEC5A: pathogenic host factors in acute viral infections. Frontiers in immunology, 10, 2867.

Xia, L. (2017). Platelet CLEC-2: a molecule with 2 faces. Blood, The Journal of the American Society of Hematology, 130(20), 2158-2160.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-CLEC2A Recombinant Antibody (CBXC-1299) (CAT#: V2LY-1206-LY106)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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