Mouse Anti-CNTLN Recombinant Antibody (CBFYC-2015) (V2LY-1206-LY526)

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Basic Information

Host Animal
Mouse
Clone
CBFYC-2015
Application
ELISA, WB
Immunogen
CNTLN (971 a.a.-1070 a.a) partial recombinant protein.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
centlein, centrosomal protein
Entrez Gene ID
UniProt ID
Function
Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
Biological Process
Centriole-centriole cohesion Source: UniProtKB
Protein localization to organelle Source: UniProtKB
Cellular Location
Centriole. Colocalizes with gamma-tubulin during interphase and mitosis. Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434).
PTM
Phosphorylated directly or indirectly by NEK2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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