Mouse Anti-COG2 Recombinant Antibody (CBYY-C2971) (V2LY-1206-LY568)

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Basic Information

Host Animal
Mouse
Clone
CBYY-C2971
Application
IP, WB
Immunogen
Recombinant COG2 of human.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.1% gelatin
Preservative
<0.1% sodium azide
Concentration
0.1 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
component of oligomeric golgi complex 2
Entrez Gene ID
UniProt ID
Function
Required for normal Golgi morphology and function.
Biological Process
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Golgi organization Source: UniProtKB
Intra-Golgi vesicle-mediated transport Source: UniProtKB
Protein transport Source: UniProtKB-KW
Cellular Location
Golgi apparatus membrane
Involvement in disease
Congenital disorder of glycosylation 2Q (CDG2Q):
A form of congenital disorder of glycosylation, a genetically heterogeneous group of autosomal recessive, multisystem disorders caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. The transmission pattern of CDG2Q is consistent with autosomal recessive inheritance.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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