Mouse Anti-COG6 Recombinant Antibody (CBFYC-2028) (V2LY-1206-LY575)
Basic Information
| Application | Note |
| WB | 1:200-1:2,000 |
| IHC | 1:150 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Glycosylation Source: UniProtKB
Intra-Golgi vesicle-mediated transport Source: GO_Central
Protein transport Source: UniProtKB-KW
A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. Clinical features of CDG2L include neonatal intractable focal seizures, vomiting, loss of consciousness, intracranial bleeding due to vitamin K deficiency, and death in infancy.
Shaheen syndrome (SHNS):
An autosomal recessive form of syndromic mental retardation. Affected individuals show severe intellectual disability, hypohidrosis, dental enamel hypoplasia, and hyperkeratosis of the palms and soles. Some may develop mild microcephaly.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Related Products
Mouse Anti-COG6 Recombinant Antibody (2D8) (CAT#: V2LY-1206-LY571)
Mouse Anti-COG6 Recombinant Antibody (1B8) (CAT#: V2LY-1206-LY573)
Mouse Anti-COG6 Recombinant Antibody (CBFYC-2027) (CAT#: V2LY-1206-LY574)
Mouse Anti-COG6 Recombinant Antibody (5B5) (CAT#: V2LY-1206-LY572)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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