Mouse Anti-CPM Recombinant Antibody (CBXC-2006) (V2LY-1206-LY966)

Name: Mouse Anti-CPM Recombinant Antibody (CBXC-2006)
SKU: V2LY-1206-LY966
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXC-2006

Application

WB, IHC

Immunogen

Recombinant protein corresponding to amino acids 124-423 of human CPM.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:2,000
IHC	1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Carboxypeptidase M

Entrez Gene ID

1368

UniProt ID

P14384

Function

Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.

Biological Process

Anatomical structure morphogenesis Source: ProtInc
Peptide metabolic process Source: GO_Central
Protein processing Source: GO_Central

Cellular Location

Cell membrane

Mamoor, S. (2021). Differential expression of carboxypeptidase M in cancers of the breast.

Shi, L., Liu, L., Lv, X., Ma, Z., Li, C., Li, Y., ... & Han, B. (2020). Identification of genetic effects and potential causal polymorphisms of CPM gene impacting milk fatty acid traits in Chinese Holstein. Animal Genetics, 51(4), 491-501.

Chu, M., Wu, S., Wang, W., Yu, Y., Zhang, M., Sang, L., ... & Wu, J. (2019). Functional variant of the carboxypeptidase M (CPM) gene may affect silica-related pneumoconiosis susceptibility by its expression: a multistage case–control study. Occupational and environmental medicine, 76(3), 169-174.

Guimarães, P. B., da Silva, R. F., Hoff, C. C., Fernandes, L., Nakaie, C. R., Chagas, J. R., ... & Pesquero, J. B. (2019). Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells. Inflammation Research, 68(10), 845-855.

Lu, D., Yao, Q., Zhan, C., Le-Meng, Z., Liu, H., Cai, Y., ... & Zhang, S. (2017). MicroRNA-146a promote cell migration and invasion in human colorectal cancer via carboxypeptidase M/src-FAK pathway. Oncotarget, 8(14), 22674.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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