Mouse Anti-CREBL2 Recombinant Antibody (CBFYC-2201) (CBMAB-C2271-FY)

Name: Mouse Anti-CREBL2 Recombinant Antibody (CBFYC-2201)
SKU: CBMAB-C2271-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYC-2201

Application

ELISA, WB

Immunogen

Full-length recombinant CREBL2.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

cAMP responsive element binding protein-like 2

Introduction

CREBL2 (CAMP Responsive Element Binding Protein Like 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding.

Entrez Gene ID

1389

UniProt ID

O60519

Alternative Names

CAMP Responsive Element Binding Protein Like 2; CAMP Responsive Element Binding Protein-Like 2

Function

Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor.

Biological Process

Cell cycle Source: UniProtKB-KW
Cell differentiation Source: UniProtKB-KW
Positive regulation of fat cell differentiation Source: UniProtKB
Positive regulation of glucose import Source: UniProtKB
Positive regulation of lipid biosynthetic process Source: UniProtKB
Positive regulation of peptidyl-serine phosphorylation Source: UniProtKB
Positive regulation of transcription, DNA-templated Source: UniProtKB
Protein stabilization Source: UniProtKB
Regulation of transcription, DNA-templated Source: GO_Central
Signal transduction Source: ProtInc
Transcription, DNA-templated Source: ProtInc

Cellular Location

Nucleus

PTM

Phosphorylated by AMPK.

Tiebe, M., Lutz, M., Senyilmaz Tiebe, D., & Teleman, A. A. (2019). Crebl2 regulates cell metabolism in muscle and liver cells. Scientific reports, 9(1), 1-12.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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