Mouse Anti-CST5 Recombinant Antibody (CBYY-C2231) (CBMAB-C3669-YY)

This product is mouse antibody that recognizes CST5. The antibody CBYY-C2231 can be used for immunoassay techniques such as: Neut, WB
See all CST5 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYY-C2231

Antibody Isotype

IgG2

Application

Neut, WB

Basic Information

Immunogen

Human recombinant Cystatin-D

Specificity

Human

Antibody Isotype

IgG2

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Protein G purified

Preservative

PBS

Concentration

Lyophilized

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Cystatin D

Entrez Gene ID

1473

UniProt ID

P28325

Alternative Names

Cytotoxic T-Lymphocyte Associated Protein 4; Insulin-Dependent Diabetes Mellitus 12; Celiac Disease 3; CTLA-4; CD152; Ligand And Transmembrane Spliced Cytotoxic T Lymphocyte Associated Antigen 4; Cytotoxic T Lymphocyte Associated Antigen 4 Short Spliced Form; Cytotoxic T-Lymphocyte-Associated Serine Esterase-4; Cytotoxic T-Lymphocyte-Associated Antigen 4; Cytotoxic T-Lymphocyte Protein 4;

Function

Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S> cathepsin H> cathepsin L> cathepsin B.

Cellular Location

Secreted

References

Mohammed, N. U. G., Khaleel, F. M., & Gorial, F. I. (2021). Cystatin D as a new diagnostic marker in rheumatoid arthritis. Gene Reports, 23, 101027.

Fujita-Yoshigaki, J., Yokoyama, M., & Katsumata-Kato, O. (2020). Switching of cargo sorting from the constitutive to regulated secretory pathway by the addition of cystatin D sequence in salivary acinar cells. American Journal of Physiology-Gastrointestinal and Liver Physiology, 319(1), G74-G86.

Wang, F., Zhang, C., Ge, W., & Zhang, G. (2019). Up‐regulated CST5 inhibits bone resorption and activation of osteoclasts in rat models of osteoporosis via suppression of the NF‐κB pathway. Journal of Cellular and Molecular Medicine, 23(10), 6744-6754.

Hill, L. J., Di Pietro, V., Hazeldine, J., Davies, D., Toman, E., Logan, A., & Belli, A. (2018). Author Correction: Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury. Scientific Reports, 8(1), 1-1.

Hill, L. J., Di Pietro, V., Hazeldine, J., Davies, D., Toman, E., Logan, A., & Belli, A. (2017). Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury. Scientific Reports, 7(1), 1-10.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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