Mouse Anti-CSTF1 Recombinant Antibody (CBFYC-2364) (V2LY-0125-LY187)

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Basic Information

Host Animal
Mouse
Clone
CBFYC-2364
Application
WB, IP, IF, ELISA
Immunogen
Amino acids 372-397 near the C-terminus of human CstF-50.
Host Species
Mouse
Specificity
Human, Mouse, Rat, Horse, Pig, Cattle, Dog
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:100-1:1,000
IP1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Gelatin & PBS
Preservative
Sodium Azide
Concentration
0.2 mg/mL
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Cleavage Stimulation Factor Subunit 1
Entrez Gene ID
UniProt ID
Function
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (PubMed:10669729).

May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (PubMed:10669729).
Biological Process
mRNA 3'-end processing Source: Reactome
mRNA splicing, via spliceosome Source: Reactome
Termination of RNA polymerase II transcription Source: Reactome
Cellular Location
Nucleus
PTM
The N-terminus is blocked.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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