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Mouse Anti-DHX34 Recombinant Antibody (E-3) (CBMAB-D0853-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
E-3
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
DExH-Box Helicase 34
Introduction
DHX34 is a member of DEAD box family. It is mapped to the glioma 19q tumor suppressor region and is a tumor suppressor candidate gene. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.
Entrez Gene ID
9704
UniProt ID
Q14147
Alternative Names
DExH-Box Helicase 34; DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 34; DEAH-Box Helicase 34; DEAH Box Protein 34; DDX34; DEAH (Asp-Glu-Ala-His) Box Polypeptide 34; Probable ATP-Dependent RNA Helicase DHX34;
Function
Probable ATP-binding RNA helicase.
Biological Process
Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: UniProtKB
Nuclear-transcribed mRNA catabolic process Source: UniProtKB
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: GO_Central
Cellular Location
Membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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