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Mouse Anti-DLEU1 Recombinant Antibody (V2-32920) (CBMAB-D1021-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Deleted In Lymphocytic Leukemia 1 (DLEU1). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all DLEU1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-32920
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
DLEU1 (AAH20692, 1 a.a. ~ 78 a.a) full-length recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
deleted in lymphocytic leukemia 1 (non-protein coding)
Introduction
DLEU1 has ubiquitous expression in testis (RPKM 1.6), colon (RPKM 1.5) and 25 other tissues
Entrez Gene ID
10301
UniProt ID
O43261
Alternative Names
BCMS; DLB1; LEU1; LEU2; XTP6; BCMS1; DLEU2; LINC00021; NCRNA00021
Function
May act as a tumor suppressor.

Lv, T., Liu, H., Wu, Y., & Huang, W. (2021). Knockdown of lncRNA DLEU1 inhibits the tumorigenesis of oral squamous cell carcinoma via regulation of miR‑149‑5p/CDK6 axis. Molecular Medicine Reports, 23(6), 1-11.

Zhao, J. L., Zhao, L. L., Niu, W. Z., Ding, X. C., & Zhang, W. L. (2020). Deleted in lymphocytic leukemia 1 promoted proliferation and apoptosis of nephroblastoma cells through regulating miR-513a-5p and RANBP2 pathway. Zhonghua Zhong liu za zhi [Chinese Journal of Oncology], 42(10), 849-855.

Li, Z., & Hou, M. (2020). lncRNA deleted in lymphocytic leukaemia 1 (DLEU1) promotes the migration and invasion of human embryonic trophoblast cells. Zygote, 28(5), 397-402.

Zhang, W., Liu, S., Liu, K., & Liu, Y. (2019). Long non‐coding RNA deleted in lymphocytic leukaemia 1 promotes hepatocellular carcinoma progression by sponging miR‐133a to regulate IGF‐1R expression. Journal of Cellular and Molecular Medicine, 23(8), 5154-5164.

Gao, S., Cai, Y., Zhang, H., Hu, F., Hou, L., & Xu, Q. (2019). Long noncoding RNA DLEU1 aggravates pancreatic ductal adenocarcinoma carcinogenesis via the miR‐381/CXCR4 axis. Journal of cellular physiology, 234(5), 6746-6757.

Feng, L., He, M., Rao, M., Diao, J., & Zhu, Y. (2019). Long noncoding RNA DLEU1 aggravates glioma progression via the miR-421/MEF2D axis. OncoTargets and therapy, 12, 5405.

Yue, G., Chen, C., Bai, L., Wang, G., Huang, Y., Wang, Y., ... & Xiao, Y. (2019). Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway. Molecular Medicine Reports, 20(5), 4551-4557.

Nishiyama, K., Maruyama, R., Niinuma, T., Kai, M., Kitajima, H., Toyota, M., ... & Suzuki, H. (2018). Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1. Cell death & disease, 9(8), 1-12.

Lee, S., Luo, W., Shah, T., Yin, C., O’Connell, T., Chung, T. H., ... & Cairo, M. S. (2017). The effects of DLEU1 gene expression in Burkitt lymphoma (BL): potential mechanism of chemoimmunotherapy resistance in BL. Oncotarget, 8(17), 27839.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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