Mouse Anti-DNAJA4 Recombinant Antibody (4B4-1F2) (CBMAB-D1271-YC)

Provided herein is a Mouse monoclonal antibody, which binds to DnaJ Heat Shock Protein Family (Hsp40) Member A4 (DNAJA4). The antibody can be used for immunoassay techniques, such as ELISA, IF, IHC-P, WB.
See all DNAJA4 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

4B4-1F2

Antibody Isotype

IgG1, κ

Application

ELISA, IF, IHC-P, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

DnaJ Heat Shock Protein Family (Hsp40) Member A4

Introduction

DNAJA4 (DnaJ Heat Shock Protein Family (Hsp40) Member A4) is a protein coding gene. It has proved that the protein has unfolded protein binding and heat shock protein binding. And a paralog is DNAJA1.

Entrez Gene ID

55466

UniProt ID

Q8WW22

Alternative Names

DnaJ Heat Shock Protein Family (Hsp40) Member A4; DnaJ (Hsp40) Homolog, Subfamily A, Member 4; DnaJ Homolog Subfamily A Member 4; MSTP104; PRO1472; MST104;

Biological Process

Negative regulation of endothelial cell migration Source: ARUK-UCL
Negative regulation of inclusion body assembly Source: UniProtKB
Positive regulation of gene expression Source: ARUK-UCL
Protein refolding Source: UniProtKB
Response to heat Source: InterPro

Cellular Location

Membrane

References

Liu, R. J., Niu, X. L., Yuan, J. P., Chen, H. D., Gao, X. H., & Qi, R. Q. (2021). DnaJA4 is involved in responses to hyperthermia by regulating the expression of F-actin in HaCaT cells. Chinese Medical Journal, 134(04), 456-462.

Wei, Z. D., Sun, Y. Z., Tu, C. X., Qi, R. Q., Huo, W., Chen, H. D., & Gao, X. H. (2020). DNAJA4 deficiency augments hyperthermia‐induced Clusterin and ERK activation: two critical protective factors of human keratinocytes from hyperthermia‐induced injury. Journal of the European Academy of Dermatology and Venereology, 34(10), 2308-2317.

Sun, Y. Z., Ren, Y., Zhang, Y. J., Han, Y., Yang, Y., Gao, Y. L., ... & Gao, X. H. (2018). DNAJA4 deficiency enhances NF-kappa B-related growth arrest induced by hyperthermia in human keratinocytes. Journal of Dermatological Science, 91(3), 256-267.

Kadakia, R. B., Zheng, Y., Zhang, Z., Zhang, W., Hou, L., & Josefson, J. (2017, April). Cord Blood DNAJA4 Hypermethylation Is Associated with Increased Neonatal Leptin, a Marker of Adiposity. In 99th Annual Meeting of the Endocrine Society. Endocrine Society.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Antibody Pairs

DNAJA4 Matched Antibody Pair (345)

DNAJA4 Matched Antibody Pair (346)

Related Products

DNAJA4 Matched Antibody Pair (346)

DNAJA4 Matched Antibody Pair (345)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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