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Mouse Anti-DNAJB5 Recombinant Antibody (10B2740) (CBMAB-D1296-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
10B2740
Antibody Isotype
IgG2a, κ
Application
ELISA, IP, WB

Basic Information

Immunogen
Recombinant human DnaJB5.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Gelatin & PBS
Preservative
Sodium Azide
Concentration
0.1 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-387

Target

Full Name
DnaJ (Hsp40) homolog, subfamily B, member 5
Introduction
DNAJB5 belongs to the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone deacetylase 4, serves as a master negative regulator of cardiac hypertrophy.
Entrez Gene ID
25822
UniProt ID
O75953
Alternative Names
DnaJ Heat Shock Protein Family (Hsp40) Member B5; DnaJ (Hsp40) Homolog, Subfamily B, Member 5; Heat Shock Protein Cognate 40; Heat Shock Protein Hsp40-2; Heat Shock Protein Hsp40-3; Hsc40; DnaJ Homolog Subfamily B Member 5; Heat Shock Cognate 40;
Biological Process
Chaperone cofactor-dependent protein refolding Source: GO_Central
Response to unfolded protein Source: UniProtKB
Cellular Location
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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