Mouse Anti-DNAL1 Recombinant Antibody (29E4) (V2LY-0425-LY661)

Basic Information
Application | Note |
WB | 1:100-1:1,000 |
IP | 1-2 µg per 100-500 µg of total protein (1 ml of cell lysate) |
IF(ICC) | 1:50-1:500 |
ELISA | 1:100-1:1,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity).
Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (PubMed:21496787).
A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Alternative Versions
Mouse Anti-DNAL1 Recombinant Antibody (29E4) (CAT#: CBMAB-D1327-YC)
Related Products
Mouse Anti-DNAL1 Recombinant Antibody (29E4) (CAT#: CBMAB-D1327-YC)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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