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Mouse Anti-DNALI1 Recombinant Antibody (2H3) (CBMAB-D1337-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Dynein Axonemal Light Intermediate Chain 1 (DNALI1). The antibody can be used for immunoassay techniques, such as ELISA, IP, WB.
See all DNALI1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2H3
Antibody Isotype
IgM, κ
Application
ELISA, IP, WB

Basic Information

Immunogen
DNALI1 (AAH46117, 1 a.a. ~ 258 a.a) full-length recombinant protein with GST tag. The immunogen sequence: MIPPADSLLK YDTPVLVSRN TEKRSPKARL LKVSPQQPGP SGSAPQPPKT KLPSTPCVPD PTKQAEEILN AILPPREWVE DTQLWIQQVS STPSTRMDVV HLQEQLDLKL QQRQARETGI CPVRRELYSQ CFDELIREVT INCAERGLLL LRVRDEIRMT IAAYQTLYES SVAFGMRKAL QAEQGKSDME RKIAELETEK RDLERQVNEQ KAKCEATEKR ESERRQVEEK KHNEEIQFLK RTNQQLKAQL EGIIAPKK
Specificity
Human
Antibody Isotype
IgM, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-258

Target

Full Name
Dynein Axonemal Light Intermediate Chain 1
Introduction
DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Entrez Gene ID
7802
UniProt ID
O14645
Alternative Names
Dynein Axonemal Light Intermediate Chain 1; Dynein, Axonemal, Light Intermediate Polypeptide 1; DJ423B22.5 (Axonemal Dynein Light Chain (Hp28)); Inner Dynein Arm, Homolog Of Clamydomonas; Inner Dynein Arm Light Chain, Axonemal; Hp28; Axonemal Dynein Light Intermediate Polypeptide 1; DJ423B22.5; P28;
Function
May play a dynamic role in flagellar motility.
Cellular Location
Cilium; Flagellum; Dynein axonemal particle
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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