Mouse Anti-DPYSL5 Recombinant Antibody (2D10) (CBMAB-D1663-YC)

Name: Mouse Anti-DPYSL5 Recombinant Antibody (2D10)
SKU: CBMAB-D1663-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2D10

Application

ELISA, IF, WB

Immunogen

Full-length recombinant DPYSL5.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
IF(ICC)	10 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-564

More Infomation

Target

Full Name

Dihydropyrimidinase Like 5

Introduction

DPYSL5 belongs to the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Entrez Gene ID

Human	56896
Mouse	65254
Rat	65208

UniProt ID

Human	Q9BPU6
Mouse	Q9EQF6
Rat	Q9JHU0

Alternative Names

Dihydropyrimidinase Like 5; UNC33-Like Phosphoprotein 6; CRMP3-Associated Molecule; CRMP-5; ULIP-6; Ulip6; CRMP5;

Function

May have a function in neuronal differentiation and/or axon growth.

Biological Process

Axon guidance Source: ProtInc
Nervous system development Source: ProtInc
Signal transduction Source: ProtInc

Cellular Location

Cytoplasm

Jeanne, M., Demory, H., Moutal, A., Vuillaume, M. L., Blesson, S., Thépault, R. A., ... & Laumonnier, F. (2021). Missense variants in DPYSL5 cause a neurodevelopmental disorder with corpus callosum agenesis and cerebellar abnormalities. The American Journal of Human Genetics, 108(5), 951-961.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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