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Mouse Anti-EAPP Recombinant Antibody (2E4) (CBMAB-CP0530-LY)

The product is antibody recognizes EAPP. The antibody 2E4 immunoassay techniques such as: WB,IF (ICC).
See all EAPP antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Monkey
Clone
2E4
Antibody Isotype
IgG1
Application
WB, IF (ICC)

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a recombinant amino-terminal fragment of human EAPP protein.
Specificity
Human, Mouse, Rat, Monkey
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
E2F associated phosphoprotein
Introduction
This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
Human55837
Mouse66266
Rat299043
Monkey714727
UniProt ID
HumanQ56P03
MouseQ5BU09
RatB5DF09
MonkeyA0A0D9RSZ1
Alternative Names
BM036; C14orf11
Research Area
May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression.
Biological Process
Negative regulation of transcription elongation from RNA polymerase II promoter Source: MGI
Positive regulation of cell population proliferation Source: MGI
Positive regulation of transcription elongation from RNA polymerase II promoter Source: MGI
Cellular Location
Nucleus; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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