Mouse Anti-EDA Recombinant Antibody (CBFYM-1081) (V2LY-0425-LY1372)

Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
May also play a role in cell adhesion (By similarity).
Isoform 1:
Binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor EDA2R.
Isoform 3:
Binds only to the receptor EDA2R.
Cell differentiation Source: UniProtKB-KW
Cell-matrix adhesion Source: Ensembl
Cytokine-mediated signaling pathway Source: UniProtKB
Gene expression Source: Ensembl
Hair follicle placode formation Source: Ensembl
Immune response Source: InterPro
Odontogenesis of dentin-containing tooth Source: UniProtKB
Pigmentation Source: Ensembl
Positive regulation of canonical Wnt signaling pathway Source: Ensembl
Positive regulation of gene expression Source: Ensembl
Positive regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl
Positive regulation of NF-kappaB transcription factor activity Source: HGNC-UCL
Positive regulation of NIK/NF-kappaB signaling Source: Ensembl
Regulation of NIK/NF-kappaB signaling Source: UniProtKB
Salivary gland cavitation Source: Ensembl
Trachea gland development Source: Ensembl
Ectodysplasin-A, secreted form: Secreted
A form of ectodermal dysplasia, a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. Characterized by sparse hair (atrichosis or hypotrichosis), abnormal or missing teeth and the inability to sweat due to the absence of sweat glands. It is the most common form of over 150 clinically distinct ectodermal dysplasias.
Tooth agenesis, selective, X-linked, 1 (STHAGX1):
A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth).
Helical: 42-62
Extracellular: 63-391
Processing by furin produces a secreted form.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Related Products
Mouse Anti-EDA Recombinant Antibody (CBFYE-0425) (CAT#: CBMAB-E0743-FY)
Mouse Anti-EDA Recombinant Antibody (CBFYE-0424) (CAT#: V2LY-0425-LY1370)
Mouse Anti-EDA Recombinant Antibody (4B3) (CAT#: CBMAB-A2440-LY)
Mouse Anti-EDA Recombinant Antibody (1E2) (CAT#: CBMAB-A2434-LY)
Mouse Anti-EDA Recombinant Antibody (8A5) (CAT#: CBMAB-A2443-LY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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