Mouse Anti-ELOF1 Recombinant Antibody (4F6) (CBMAB-A2579-LY)

Name: Mouse Anti-ELOF1 Recombinant Antibody (4F6)
SKU: CBMAB-A2579-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

4F6

Application

WB, ELISA

Immunogen

ELOF1 full-length recombinant protein.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

elongation factor 1 homolog (S. cerevisiae)

Entrez Gene ID

84337

UniProt ID

P60002

Alternative Names

ELF1

Research Area

Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

Biological Process

Chromatin-mediated maintenance of transcription Source: GO_Central
Transcription elongation from RNA polymerase II promoter Source: GO_Central

Cellular Location

Nucleus

Carnie, C. J., & Jackson, S. P. (2021). The ELOF (1) ant in the room of TCR. Nature Cell Biology, 23(6), 584-586.

Geijer, M. E., Zhou, D., Selvam, K., Steurer, B., Mukherjee, C., Evers, B., ... & Marteijn, J. A. (2021). Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability. Nature cell biology, 23(6), 608-619.

van der Weegen, Y., de Lint, K., van den Heuvel, D., Nakazawa, Y., Mevissen, T. E., van Schie, J. J., ... & Luijsterburg, M. S. (2021). ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation. Nature Cell Biology, 23(6), 595-607.

Geijer, M. E., Zhou, D., Selvam, K., Steurer, B., Mukherjee, C., Evers, B., ... & Marteijn, J. A. (2021). Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability. Nature Cell Biology, 23(7), 809-809.

Tellier, A. P., Archambault, D., Tremblay, K. D., & Mager, J. (2019). The elongation factor Elof1 is required for mammalian gastrulation. PloS one, 14(7), e0219410.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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