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  • Mouse Anti-ERC2 Recombinant Antibody (1191)

Mouse Anti-ERC2 Recombinant Antibody (1191) (V2LY-0825-LY644)

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Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
1191
Application
IP
Immunogen
Human ERC2.
Host Species
Mouse
Specificity
Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
IP1:100-1:200

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
ELKS/RAB6-Interacting/CAST Family Member 2
Entrez Gene ID
Human26059
Mouse238988
UniProt ID
HumanO15083
MouseQ6PH08
Alternative Names
CAST; CAST1; ELKSL; Spc110; SPBC110
Research Area
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Function
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Biological Process
Maintenance of presynaptic active zone structure
Regulation of calcium-dependent activation of synaptic vesicle fusion
Regulation of presynaptic cytosolic calcium ion concentration
Synaptic vesicle priming
Cellular Location
Cytoplasm
Synapse
Presynaptic active zone
Cytoplasm, cytoskeleton
Note: In neurons, localized to synapses, and colocalizes with PCLO. Localized to the active zone of presynaptic density (By similarity).

Cheng, P., Chen, K., Zhang, S., Mu, K. T., Liang, S., & Zhang, Y. (2021). IDH1 R132C and ERC2 L309I Mutations Contribute to the Development of Maffucci’s Syndrome. Frontiers in Endocrinology, 12.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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