Mouse Anti-ERCC8 Recombinant Antibody (E1738) (V2LY-0825-LY678)
Basic Information
| Application | Note |
| WB | 1:2,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
DNA duplex unwinding Source: GOC
Double-strand break repair via classical nonhomologous end joining Source: UniProtKB
Nucleotide-excision repair Source: UniProtKB
Positive regulation of DNA repair Source: UniProtKB
Proteasome-mediated ubiquitin-dependent protein catabolic process Source: UniProtKB
Protein autoubiquitination Source: UniProtKB
Protein polyubiquitination Source: UniProtKB
Response to oxidative stress Source: UniProtKB
Response to UV Source: UniProtKB
Single strand break repair Source: UniProtKB
Transcription-coupled nucleotide-excision repair Source: MGI
A rare disorder characterized by cutaneous sensitivity to sunlight, abnormal and slow growth, cachectic dwarfism, progeroid appearance, progressive pigmentary retinopathy and sensorineural deafness. There is delayed neural development and severe progressive neurologic degeneration resulting in mental retardation. Two clinical forms are recognized: in the classical form or Cockayne syndrome type 1, the symptoms are progressive and typically become apparent within the first few years or life; the less common Cockayne syndrome type 2 is characterized by more severe symptoms that manifest prenatally. Cockayne syndrome shows some overlap with certain forms of xeroderma pigmentosum. Unlike xeroderma pigmentosum, patients with Cockayne syndrome do not manifest increased freckling and other pigmentation abnormalities in the skin and have no significant increase in skin cancer.
UV-sensitive syndrome 2 (UVSS2):
An autosomal recessive disorder characterized by cutaneous photosensitivity and mild freckling in the absence of neurological abnormalities or skin tumors.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Related Products
Mouse Anti-ERCC8 Recombinant Antibody (E1737) (CAT#: V2LY-0825-LY679)
Rabbit Anti-ERCC8 Recombinant Antibody (CBFYE-1171) (CAT#: V2LY-0825-LY682)
Mouse Anti-ERCC8 Recombinant Antibody (CBFYE-1168) (CAT#: V2LY-0825-LY680)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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