Mouse Anti-FOXN2 Recombinant Antibody (EG1234) (V2LY-0925-LY2948)

Name: Mouse Anti-FOXN2 Recombinant Antibody (EG1234)
SKU: V2LY-0925-LY2948
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

EG1234

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 62-85 within an internal region of mouse FOXN2.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgM, κ

Clonality

Monoclonal

Application Notes

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

Gelatin & PBS

Preservative

Sodium azide

Concentration

0.2 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Forkhead Box N2

Entrez Gene ID

3344

UniProt ID

P32314

Function

Binds to the purine-rich region in HTLV-I LTR.

Biological Process

Regulation of transcription, DNA-templated Source: GO_Central
Skeletal muscle cell differentiation Source: Ensembl

Cellular Location

Nucleus

Jeong, S., Kim, S. A., & Ahn, S. G. (2022). HOXC6-Mediated miR-188-5p expression induces cell migration through the inhibition of the tumor suppressor FOXN2. International Journal of Molecular Sciences, 23(1), 9.

Liu, X. H., Liu, L. P., Xu, X. M., Hua, M., Kang, Q., Li, A., & Huang, L. (2021). FOXN2 suppresses the proliferation and invasion of human hepatocellular carcinoma cells. Eur. Rev. Med. Pharmacol. Sci, 25, 731-737.

Santibanez, B., Oliveira, S., Duggan, K., Lu, K., & Johnson, K. (2019). Abstract C49: Knockdown of FOXN2 enhances adhesion and reduces migration in pancreatic cancer cells. Cancer Research, 79(24_Supplement), C49-C49.

Dai, S. G., Guo, L. L., Xia, X., & Pan, Y. (2019). Long non-coding RNA WT1-AS inhibits cell aggressiveness via miR-203a-5p/FOXN2 axis and is associated with prognosis in cervical cancer. Eur Rev Med Pharmacol Sci, 23(2), 486-495.

Ye, H., & Duan, M. (2019). FOXN2 is downregulated in breast cancer and regulates migration, invasion, and epithelial–mesenchymal transition through regulation of SLUG. Cancer Management and Research, 11, 525.

Ma, J., Lu, Y., Zhang, S., Li, Y., Huang, J., Yin, Z., ... & Xu, S. (2018). β-Trcp ubiquitin ligase and RSK2 kinase-mediated degradation of FOXN2 promotes tumorigenesis and radioresistance in lung cancer. Cell Death & Differentiation, 25(8), 1473-1485.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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