Rabbit Anti-FOXR1 Recombinant Antibody (EG1240) (CBMAB-EN1498-LY)

The product is antibody recognizes FOXR1. The antibody EG1240 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:20000.
See all FOXR1 antibodies

Datasheet

Summary

Host Animal

Rabbit

Specificity

Human, Mouse

Clone

EG1240

Antibody Isotype

IgG

Application

WB: 1:500~1:1000 ELISA: 1:20000

Basic Information

Immunogen

The antibody was produced against synthesized peptide derived from internal of human FOXR1.

Specificity

Human, Mouse

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

forkhead box R1

Introduction

This gene encodes a member of the forkhead box (FOX) family of transcription factors. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 aa. Many FOX transcription factors play roles in determining cell fates during early development. This forkhead box protein lacks the C-terminal basic region found in many other FOX family members. It is located within the 11q23.3 region which is commonly deleted in neuroblastomas.

Entrez Gene ID

Human	283150
Mouse	382074

UniProt ID

Human	Q6PIV2
Mouse	Q3UTB7

Alternative Names

FOXN5; DLNB13

Cellular Location

Nucleus

References

Socha, M., Szczygieł, J., Brzuska, E., Sokołowska-Mikołajczyk, M., Stonawski, B., & Grzesiak, M. (2021). The effect of Roundup on embryonic development, early foxr1 and hsp70 gene expression and hatching of common carp (Cyprinus carpio L.). Theriogenology, 175, 163-169.

Mota, A., Waxman, H. K., Hong, R., Lagani, G. D., Niu, S. Y., Bertherat, F. L., ... & Ho, A. (2021). FOXR1 regulates stress response pathways and is necessary for proper brain development. PLoS Genetics, 17(11), e1009854.

Gimenez, T. M., Neves, N. H., Santos, A. R., Marchi, F. A., Kulikowski, L., Cristofani, L. M., ... & Filho, V. O. (2018). Abstract B13: BLM, FOXO3, FOXK2, FOXM1, FOXR1 genes as therapeutic targets to neuroblastoma. Clinical Cancer Research, 24(1_Supplement), B13-B13.

Cheung, C. T., Patinote, A., Guiguen, Y., & Bobe, J. (2018). foxr1 is a novel maternal-effect gene in fish that is required for early embryonic success. PeerJ, 6, e5534.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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