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Mouse Anti-FOXR2 (AA 1-312) Recombinant Antibody (CBXF-0895) (CBMAB-F0306-CQ)

This product is a mouse antibody that recognizes FOXR2 (AA 1-312). The antibody CBXF-0895 can be used for immunoassay techniques such as: ELISA, ICC, IHC, WB.
See all FOXR2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0895
Antibody Isotype
IgG1
Application
ELISA, ICC, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-312

Target

Full Name
forkhead box R2
Introduction
FOXR2 (Forkhead Box R2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is FOXR1.
Entrez Gene ID
139628
UniProt ID
Q6PJQ5
Alternative Names
Forkhead Box R2; Forkhead Box Protein N6; FOXN6; Forkhead Box Protein R2;
Cellular Location
Nucleus

Shimazaki, K., Kurokawa, R., Franson, A., Kurokawa, M., Baba, A., Bou‐Maroun, L., ... & Moritani, T. (2023). Neuroimaging features of FOXR2‐activated CNS neuroblastoma: A case series and systematic review. Journal of Neuroimaging.

Tsai, J. W., Cejas, P., Wang, D. K., Patel, S., Wu, D. W., Arounleut, P., ... & Phoenix, T. N. (2022). FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits. Cancer research, 82(17), 2980-3001.

Flasch, D. A., Chen, X., Ju, B., Li, X., Dalton, J., Mulder, H. L., ... & Zhang, J. (2022). Somatic LINE-1 promoter acquisition drives oncogenic FOXR2 activation in pediatric brain tumor. Acta Neuropathologica, 143(5), 605-607.

Chen, X., Chen, H., Liu, M., Xiong, J., & Song, Z. (2021). Long noncoding RNA LINC00520 accelerates lung adenocarcinoma progression via miR-1252-5p/FOXR2 pathway. Human Cell, 34, 478-490.

Schmitt-Hoffner, F., van Rijn, S., Toprak, U. H., Mauermann, M., Rosemann, F., Heit-Mondrzyk, A., ... & Kool, M. (2021). FOXR2 stabilizes MYCN protein and identifies non–MYCN-amplified neuroblastoma patients with unfavorable outcome. Journal of Clinical Oncology, 39(29), 3217-3228.

Korshunov, A., Okonechnikov, K., Schmitt-Hoffner, F., Ryzhova, M., Sahm, F., Stichel, D., ... & von Deimling, A. (2021). Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation. Acta neuropathologica communications, 9, 1-12.

Xia, D., Chen, Z., & Liu, Q. (2021). Circ-PGC increases the expression of FOXR2 by targeting miR-532-3p to promote the development of non-small cell lung cancer. Cell Cycle, 20(21), 2195-2209.

Zhang, S., Cheng, J., Quan, C., Wen, H., Feng, Z., Hu, Q., ... & Wu, X. (2020). circCELSR1 (hsa_circ_0063809) contributes to paclitaxel resistance of ovarian cancer cells by regulating FOXR2 expression via miR-1252. Molecular Therapy-Nucleic Acids, 19, 718-730.

Łastowska, M., Trubicka, J., Sobocińska, A., Wojtas, B., Niemira, M., Szałkowska, A., ... & Matyja, E. (2020). Molecular identification of CNS NB-FOXR2, CNS EFT-CIC, CNS HGNET-MN1 and CNS HGNET-BCOR pediatric brain tumors using tumor-specific signature genes. Acta neuropathologica communications, 8(1), 1-14.

Tian, X., Zhang, L., Jiao, Y., Chen, J., Shan, Y., & Yang, W. (2019). CircABCB10 promotes nonsmall cell lung cancer cell proliferation and migration by regulating the miR‐1252/FOXR2 axis. Journal of Cellular Biochemistry, 120(3), 3765-3772.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

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