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Mouse Anti-FRY Recombinant Antibody (CBXF-0909) (CBMAB-F0488-CQ)

This product is a mouse antibody that recognizes FRY. The antibody CBXF-0909 can be used for immunoassay techniques such as: ELISA, WB.
See all FRY antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0909
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FRY Microtubule Binding Protein
Introduction
FRY (FRY Microtubule Binding Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is FRYL.
Entrez Gene ID
10129
UniProt ID
Q5TBA9
Alternative Names
FRY Microtubule Binding Protein; C13orf14; Chromosome 13 Open Reading Frame 14; Furry Homolog (Drosophila); Protein Furry Homolog; WUGSC:H_2G3A.1; Furry Homolog;
Function
Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation.
Biological Process
Cell morphogenesis Source: GO_Central
Negative regulation of tubulin deacetylation Source: Ensembl
Neuron projection development Source: GO_Central
Cellular Location
Cytoplasm; Centrosome; Spindle pole. Distributed diffusely throughout the cytoplasm in interphase. Localizes to the separating centrosomes in prophase, to the spindle poles and spindle microtubules in prometaphase to metaphase, to spindle microtubules in anaphase and to the distal sections of the midbody in cytokinesis. Colocalizes with PLK1 to separating centrosomes and spindle poles from prophase to metaphase in mitosis, but not in other stages of the cell cycle.
PTM
Phosphorylated by AURKA, CDK1 and PLK1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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