Mouse Anti-FUBP3 Recombinant Antibody (7B10) (CBMAB-A3223-LY)

The product is antibody recognizes FUBP3. The antibody 7B10 immunoassay techniques such as: WB, ELISA.
See all FUBP3 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

7B10

Antibody Isotype

IgG2a, κ

Application

WB, ELISA

Basic Information

Immunogen

FUBP3 (AAH07874.1, 152 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

far upstream element binding protein 3

Entrez Gene ID

8939

UniProt ID

Q96I24

Alternative Names

FBP3

Function

May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.

Biological Process

Positive regulation of gene expression Source: UniProtKB
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of gene expression Source: GO_Central
Transcription, DNA-templated Source: UniProtKB

Cellular Location

Nucleus

References

Sharma, M., Anandram, S., Ross, C., & Srivastava, S. (2023). FUBP3 regulates chronic myeloid leukaemia progression through PRC2 complex regulated PAK1‐ERK signalling. Journal of Cellular and Molecular Medicine, 27(1), 15-29.

Dong, S., Kong, N., Wang, C., Li, Y., Sun, D., Qin, W., ... & Shan, T. (2022). FUBP3 degrades the porcine epidemic diarrhea virus nucleocapsid protein and induces the production of type I interferon. Journal of Virology, 96(13), e00618-22.

Li, J., Zhang, Z., Guo, K., Wu, S., Guo, C., Zhang, X., & Wang, Z. (2022). Identification of a key glioblastoma candidate gene, FUBP3, based on weighted gene co-expression network analysis. BMC neurology, 22(1), 1-10.

Yao, Q., Xie, Y., Xu, D., Qu, Z., Wu, J., Zhou, Y., ... & Zhang, X. L. (2022). Lnc-EST12, which is negatively regulated by mycobacterial EST12, suppresses antimycobacterial innate immunity through its interaction with FUBP3. Cellular & Molecular Immunology, 19(8), 883-897.

Xu, P., Tong, W., & Chen, Y. M. (2021). FUSE binding protein FUBP3 is a potent regulator in Japanese encephalitis virus infection. Virology Journal, 18, 1-11.

Gao, Q., Zhou, R., Meng, Y., Duan, R., Wu, L., Li, R., ... & Zhao, L. (2020). Long noncoding RNA CMPK2 promotes colorectal cancer progression by activating the FUBP3–c-Myc axis. Oncogene, 39(19), 3926-3938.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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