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Mouse Anti-GABRA3 Recombinant Antibody (CBLG1-453) (CBMAB-G1661-LY)

This product is antibody recognizes GABRA3. The antibody CBLG1-453 immunoassay techniques such as: ELISA.
See all GABRA3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-453
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
GABRA3 (AAH28629.1, 1 a.a. ~ 492 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
gamma-aminobutyric acid (GABA) A receptor, alpha 3
Introduction
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
Entrez Gene ID
2556
UniProt ID
P34903
Alternative Names
Gamma-Aminobutyric Acid Type A Receptor Alpha3 Subunit; Gamma-Aminobutyric Acid (GABA) A Receptor; Alpha 3; GABA(A) Receptor Subunit Alpha-3; GABA(A) Receptor; Alpha 3;
Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Biological Process
Chemical synaptic transmission Source: GO_Central
Chloride transmembrane transport Source: GO_Central
Gamma-aminobutyric acid signaling pathway Source: GO_Central
Ion transmembrane transport Source: GO_Central
Nervous system process Source: GO_Central
Regulation of membrane potential Source: GO_Central
Regulation of postsynaptic membrane potential Source: GO_Central
Signal transduction Source: GO_Central
Synaptic transmission, GABAergic Source: GO_Central
Cellular Location
Postsynaptic cell membrane; Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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