Rabbit Anti-GABRA5 Recombinant Antibody (
5C11) (V2LY-0725-LY1244)
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                                                Positive WB detected in: Ntera-2 whole cell lysate, HEK293 whole cell lysate
All lanes: GABA A Receptor alpha 5 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 53 kDa
Observed band size: 70 kDa
 
                                                Basic Information
| Application | Note | 
| WB | 1:500-1:5,000 | 
| IHC | 1:50-1:200 | 
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
May be involved in GABA-A receptor assembly, and GABA-A receptor immobilization and accumulation by gephyrin at the synapse (PubMed:31056671).
Behavioral fear response Source: Ensembl
Brain development Source: Ensembl
Chemical synaptic transmission Source: GO_Central
Chloride transmembrane transport Source: GO_Central
Cochlea development Source: Ensembl
Gamma-aminobutyric acid signaling pathway Source: GO_Central
Inner ear receptor cell development Source: Ensembl
Innervation Source: Ensembl
Ion transmembrane transport Source: GO_Central
Negative regulation of neuron apoptotic process Source: Ensembl
Nervous system process Source: GO_Central
Regulation of membrane potential Source: GO_Central
Regulation of postsynaptic membrane potential Source: GO_Central
Sensory perception of sound Source: Ensembl
Signal transduction Source: GO_Central
Synaptic transmission, GABAergic Source: GO_Central
A form of epileptic encephalopathy, a heterogeneous group of severe early-onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. DEE79 is an autosomal dominant form characterized by onset of refractory seizures in the first months of life. Brain imaging may show hypomyelination, cerebral atrophy and thinning of the corpus callosum.
5C11)?
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                                            Please try the standard protocols which include: protocols, troubleshooting and guide.
                                            
                                            Enzyme-linked Immunosorbent Assay (ELISA)
                                            
                                            
                                            Flow Cytometry
                                            
                                            
                                            Immunofluorescence (IF)
                                            
                                            
                                            Immunohistochemistry (IHC)
                                            
                                            
                                            Immunoprecipitation (IP)
                                            
                                            
                                            Western Blot (WB)
                                            
                                            
                                            Enzyme Linked Immunospot (ELISpot)
                                            
                                            
                                            Proteogenomic
                                            
                                            
                                            Other Protocols
                                            
                                            
                                        
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Mouse Anti-GABRA5 (AA 368-419) Recombinant Antibody (CBFYH-2864) (CAT#: CBMAB-H0291-FY)
Mouse Anti-GABRA5 Recombinant Antibody (S415-24) (CAT#: CBMAB-G0128-LY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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