Mouse Anti-GADD45B Recombinant Antibody (CBLG1-2528) (V2LY-1225-LY594)

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Basic Information

Host Animal
Mouse
Clone
CBLG1-2528
Application
WB, IP, IF, ELISA
Immunogen
Amino acids 133-160 at the C-terminus of human GADD45β.
Host Species
Mouse
Specificity
Human, Mouse, Rat, Horse, Dog, Cattle
Antibody Isotype
IgM, κ
Clonality
Monoclonal
Application Notes
ApplicationNote
ELISA1:100-1:1,000
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, gelatin
Preservative
Sodium azide
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
GROWTH ARREST AND DNA DAMAGE INDUCIBLE BETA
Entrez Gene ID
Human4616
Mouse17873
Rat299626
UniProt ID
HumanO75293
MouseP22339
RatQ5U3Z2
Function
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Biological Process
Activation of MAPKKK activity Source: UniProtKB
Apoptotic process Source: UniProtKB-KW
Cell differentiation Source: UniProtKB-KW
Negative regulation of protein kinase activity Source: Ensembl
Positive regulation of apoptotic process Source: UniProtKB
Positive regulation of JNK cascade Source: UniProtKB
Positive regulation of p38MAPK cascade Source: UniProtKB
Regulation of cell cycle Source: GO_Central
Cellular Location
Nucleus; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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