Mouse Anti-GADD45G Recombinant Antibody (2G6) (CBMAB-G1793-LY)

Name: Mouse Anti-GADD45G Recombinant Antibody (2G6)
SKU: CBMAB-G1793-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2G6

Application

IHC-P

Immunogen

Full length human recombinant protein of human GADD45G(NP_006696) produced in HEK293T cell.ImmunogenType: Recombinant protein

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/mL

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

growth arrest and DNA damage inducible gamma

Introduction

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]

Entrez Gene ID

10912

UniProt ID

O95257

Alternative Names

Growth Arrest And DNA Damage Inducible Gamma; DNA Damage-Inducible Transcript 2 Protein; Cytokine-Responsive Protein CR6; Gadd-Related Protein; 17 KD; DDIT-2; DDIT2; CR6;

Function

Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.

Biological Process

Activation of MAPKKK activity Source: UniProtKB
Apoptotic process Source: UniProtKB-KW
Cell differentiation Source: UniProtKB-KW
Positive regulation of apoptotic process Source: UniProtKB
Positive regulation of cold-induced thermogenesis Source: YuBioLab
Positive regulation of JNK cascade Source: UniProtKB
Positive regulation of p38MAPK cascade Source: UniProtKB
Regulation of cell cycle Source: GO_Central

Cellular Location

Nucleus; Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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