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Rabbit Anti-GBP4 Recombinant Antibody (EG1297) (CBMAB-EN1568-LY)

The product is antibody recognizes GBP4. The antibody EG1297 immunoassay techniques such as: IHC: 1:50~1:100 ELISA: 1:40000.
See all GBP4 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1297
Antibody Isotype
IgG
Application
IHC: 1:50~1:100 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human GBP4.
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Guanylate Binding Protein 4
Introduction
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008]
Entrez Gene ID
115361
UniProt ID
Q96PP9
Alternative Names
Guanylate Binding Protein 4; Guanine Nucleotide-Binding Protein 4; GTP-Binding Protein 4; GBP-4; Guanylate-Binding Protein 4; EC 3.6.5.-; Mpa2;
Function
Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation (By similarity).
Biological Process
Cellular response to interferon-gamma Source: UniProtKB
Defense response to Gram-positive bacterium Source: GO_Central
Defense response to protozoan Source: GO_Central
Cellular Location
Golgi apparatus membrane; Cytoplasm; Nucleus; Perinuclear region. Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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