Rabbit Anti-GGH Recombinant Antibody (EG1308) (CBMAB-EN1584-LY)

Name: Rabbit Anti-GGH Recombinant Antibody (EG1308)
SKU: CBMAB-EN1584-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

EG1308

Application

WB: 1:500~1:1000 ELISA: 1:10000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human GGH.

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Gamma-Glutamyl Hydrolase

Introduction

This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008]

Entrez Gene ID

8836

UniProt ID

Q92820

Alternative Names

Gamma-Glutamyl Hydrolase; Gamma-Glu-X Carboxypeptidase; Conjugase; GH; Gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase); Folylpolygammaglutamyl Hydrolase; EC 3.4.19.9;

Function

Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.

Biological Process

Poly-gamma-glutamate metabolic process Source: Ensembl
Response to drug Source: Ensembl
Response to ethanol Source: Ensembl
Response to insulin Source: Ensembl
Response to zinc ion Source: Ensembl
Tetrahydrofolylpolyglutamate metabolic process Source: GO_Central

Cellular Location

Lysosome; Extracellular space; Melanosome. While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rabbit Anti-GGH Recombinant Antibody (EG1308) (CAT#: V2LY-1225-LY1169)

Related Products

Rabbit Anti-GGH Recombinant Antibody (EG1308) (CAT#: V2LY-1225-LY1169)

Human Recombinant GGH protein, His Tag (CAT#: V2LY-0526-LY4300)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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