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Rat Anti-GINS4 Recombinant Antibody (ASF3-3-4) (CBMAB-G3505-LY)

This product is antibody recognizes GINS4. The antibody ASF3-3-4 immunoassay techniques such as: ICC, IHC, WB.
See all GINS4 antibodies

Summary

Host Animal
Rat
Specificity
Human
Clone
ASF3-3-4
Antibody Isotype
IgG
Application
ICC, IHC, WB

Basic Information

Immunogen
SLD5 antibody was raised in rats which were immunized with murine SLD5. Rat spleen cells were isolated and fused with mouse melanoma in order to establish hybridoma cells
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GINS Complex Subunit 4
Introduction
The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Entrez Gene ID
84296
UniProt ID
Q9BRT9
Alternative Names
GINS Complex Subunit 4; SLD5; DNA Replication Complex GINS Protein SLD5; GINS Complex Subunit 4 (Sld5 Homolog); SLD5 Homolog;
Function
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA.
Biological Process
DNA-dependent DNA replication Source: InterPro
Double-strand break repair via break-induced replication Source: GO_Central
Inner cell mass cell proliferation Source: Ensembl
Cellular Location
Cytoplasm; Nucleus; Chromosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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