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Mouse Anti-GKAP1 Recombinant Antibody (1B9) (CBMAB-G3610-LY)

This product is antibody recognizes GKAP1. The antibody 1B9 immunoassay techniques such as: ELISA, IHC-P, WB.
See all GKAP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B9
Antibody Isotype
IgG1, κ
Application
ELISA, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
G kinase anchoring protein 1
Introduction
This gene encodes a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse protein has been found to localize with the Golgi and recruit cGMP-dependent protein kinase I alpha to the Golgi in mouse testes. It is thought to play a role in germ cell development. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Entrez Gene ID
UniProt ID
Alternative Names
G Kinase Anchoring Protein 1; CGMP-Dependent Protein Kinase-Anchoring Protein Of 42 KDa; CGMP-Dependent Protein Kinase Anchoring Protein 42kDa; GKAP42; Protein Kinase Anchoring Protein GKAP42; G Kinase-Anchoring Protein 1; FKSG21;
Function
Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.
Biological Process
Positive regulation of insulin receptor signaling pathway Source: UniProtKB
Signal transduction Source: UniProtKB
Cellular Location
Golgi apparatus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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