Mouse Anti-GLRB Recombinant Antibody (CBT2708) (V2LY-0625-LY816)
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Basic Information
| Application | Note |
| WB | 1:500-1:2,000 |
| ICC | 1:200-1:1,000 |
| FC | 1:200-1:400 |
| ELISA | 1:10,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357).
Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346).
Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).
Adult walking behavior Source: Ensembl
Chemical synaptic transmission Source: UniProtKB
Chloride transmembrane transport Source: UniProtKB
Gamma-aminobutyric acid receptor clustering Source: Ensembl
Ion transmembrane transport Source: GO_Central
Ion transport Source: UniProtKB
Nervous system development Source: UniProtKB
Nervous system process Source: GO_Central
Neuropeptide signaling pathway Source: UniProtKB
Regulation of membrane potential Source: GO_Central
Response to amino acid Source: GO_Central
Righting reflex Source: Ensembl
Signal transduction Source: GO_Central
Startle response Source: UniProtKB
Synaptic transmission, glycinergic Source: GO_Central
Visual perception Source: Ensembl
A neurologic disorder characterized by muscular rigidity of central nervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpected acoustic or tactile stimuli.
Helical: 269-290
Cytoplasmic: 291-295
Helical: 296-316
Extracellular: 317-327
Helical: 328-348
Cytoplasmic: 349-475
Helical: 476-496
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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